Bio-organisms are a serious threat to mankind today. With the increasing resistance to antibiotics and few discoveries in new antibiotics, the healthcare risks of individuals and societies have increased manifold. Coupled to this, constant mutations in microbes need a different dimension to counter such bio-organisms. Alongside healthcare problems, deliberate use of bio-organisms as agents of terror is a threat that has no counter today. This paper presents ‘Whiff Bio-Spray,’ a breakthrough solution to neutralize these bio-organisms through the use of active plant extracts.